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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
25.76
Human Site:
S299
Identified Species:
35.42
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S299
V
S
G
P
M
P
D
S
Y
S
P
R
Y
V
E
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S299
V
S
G
P
M
P
D
S
Y
S
P
R
Y
V
E
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
R216
L
S
R
E
A
F
L
R
E
V
W
Q
W
K
E
Dog
Lupus familis
XP_538837
1256
139671
S299
V
S
G
T
M
P
D
S
Y
S
P
Q
Y
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S298
V
S
G
A
M
P
D
S
Y
S
P
Q
Y
V
E
Rat
Rattus norvegicus
Q04462
1264
140350
S299
V
S
G
T
M
P
D
S
Y
S
P
Q
Y
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
R138
L
E
D
H
L
R
L
R
T
F
L
V
G
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
S280
V
S
G
P
M
P
D
S
Y
S
P
Q
Y
V
E
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
V248
K
F
H
S
S
C
C
V
G
I
A
S
H
T
S
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S248
V
V
S
P
L
P
D
S
Y
S
P
Q
Y
V
E
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
G202
K
L
S
R
H
D
L
G
R
E
K
F
I
E
R
Honey Bee
Apis mellifera
XP_395202
1043
121057
D196
E
E
Q
K
T
R
H
D
I
G
R
E
N
F
I
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
K203
N
Q
E
V
W
H
W
K
N
E
K
G
D
V
I
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
E255
I
A
T
Q
V
V
V
E
K
Q
I
H
H
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
K247
V
G
R
E
E
F
V
K
E
V
W
K
W
K
N
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
R247
K
Q
I
W
A
K
D
R
K
T
R
H
D
Y
G
Red Bread Mold
Neurospora crassa
P28350
1093
123334
R244
K
I
R
Q
E
L
G
R
E
K
F
T
D
L
V
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
86.6
N.A.
0
N.A.
93.3
0
73.3
0
0
6.6
0
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
20
N.A.
100
6.6
86.6
0
0
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
12
0
0
0
0
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
6
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
6
48
6
0
0
0
0
18
0
6
% D
% Glu:
6
12
6
12
12
0
0
6
18
12
0
6
0
18
48
% E
% Phe:
0
6
0
0
0
12
0
0
0
6
6
6
0
6
0
% F
% Gly:
0
6
36
0
0
0
6
6
6
6
0
6
6
0
6
% G
% His:
0
0
6
6
6
6
6
0
0
0
0
12
12
0
0
% H
% Ile:
6
6
6
0
0
0
0
0
6
6
6
0
6
0
12
% I
% Lys:
24
0
0
6
0
6
0
12
12
6
12
6
0
12
6
% K
% Leu:
12
6
0
0
12
6
18
0
0
0
6
0
0
6
0
% L
% Met:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
6
0
0
0
6
0
6
% N
% Pro:
0
0
0
24
0
42
0
0
0
0
42
0
0
0
0
% P
% Gln:
0
12
6
12
0
0
0
0
0
6
0
36
0
0
0
% Q
% Arg:
0
0
18
6
0
12
0
24
6
0
12
12
0
0
6
% R
% Ser:
0
42
12
6
6
0
0
42
0
42
0
6
0
0
6
% S
% Thr:
0
0
6
12
6
0
0
0
6
6
0
6
0
6
0
% T
% Val:
48
6
0
6
6
6
12
6
0
12
0
6
0
48
6
% V
% Trp:
0
0
0
6
6
0
6
0
0
0
12
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
42
0
0
0
42
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _